The present report is being submitted pursuant to General Assembly resolutions 71/244 of 21 December 2016, and to resolution 71/318 of 28 August 2017, by which the Assembly decided to convene a second High-level United Nations Conference on South-South Cooperation at the highest possible level, and that the Conference would be held in Buenos Aires from 20 to 22 March 2019. The scope of the Conference will be to review the trends in South-South and triangular cooperation, including the progress made by the international community, in particular the United Nations, in supporting and promoting such cooperation and identifying new opportunities, as well as challenges and suggestions to overcome them. In order to inform discussions at the Conference, the present report reviews the implementation of the Buenos Aires Plan of Action since its inception by Member States, United Nations system entities and other stakeholders. In keeping with the overarching theme of the Conference, “Role of South-South cooperation and the implementation of the 2030 Agenda for Sustainable Development, challenges and opportunities”, as well as the sub-themes, the report also reviews actions at the national, regional, interregional and global levels. Against the background of lessons learned over the past 40 years, the report highlights key priorities for South-South cooperation in the years ahead.